![]() Wagner PD (2008) Causes of a high physiological dead space in critically ill patients. J Appl Physiol 55:1550–1557īreen PH, Mazumdar B, Skinner SC (1996) How does experimental pulmonary embolism decrease CO2 elimination? Respir Physiol 105:217–224ĭrummond GB, Fletcher R (2006) Deadspace: invasive or not? Br J Anaesth 96:4–7. The physiologic dead space can be measured by determining the dead space to tidal volume ratio using the Bohr equation (Equation 4): VDVT 14 Pa CO2. Anesthesiology 31:575–577Ĭoffey RL, Albert RK, Robertson HT (1983) Mechanisms of physiological dead space response to PEEP after acute oleic acid lung injury. Physiological dead space volume (Bohr equation) Assumptions Environmental air CO2 0 (actual amount 0. Kuwabara S, Duncalf D (1969) Effect of anatomic shunt on physiologic dead space-to-tidal volume ratio––a new equation. used to calculate the alveolar Po2 (see the alveolar gas equation given earlier). Tusman G, Sipmann FS, Borges JB, Hedenstierna G, Bohm SH (2011) Validation of Bohr dead space measured by volumetric capnography. Physiologic dead space is equal to the anatomic plus the alveolar dead.
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